The absence of the São José dos Campos native is a significant blow to Míchel Sánchez's tactical plans. The Manchester City loanee had become a permanent fixture in the starting lineup, completing 90 minutes in 21 consecutive league matches.

Alejandro Francés is the leading candidate to fill the void in central defense. The former Zaragoza player previously replaced Reis during the first-leg match at San Mamés, delivering a strong performance characterized by effective coverage and defensive speed.

Other alternatives for the manager include veteran David López, though his lack of match fitness—having not played since August 30th—makes a starting role unlikely. The team currently sits six points clear of the relegation zone heading into the weekend.