Study detects 42 chemicals in human semen harmful to male fertility

Research by IDAEA-CSIC and URV identifies everyday toxic compounds affecting sperm quality in men.

Image of a scientific laboratory with samples and microscopes.
IA

Image of a scientific laboratory with samples and microscopes.

Researchers from IDAEA-CSIC and the Rovira i Virgili University (URV) have identified 42 everyday chemical compounds in human semen that negatively impact male fertility.

The study, published in the journal Exposome, analyzed samples from 48 healthy men in Tarragona aged 18 to 40. Using high-resolution mass spectrometry, the team mapped the chemical exposome and its potential link to declining sperm quality over recent decades.

"Although our study does not allow establishing causal relationships, it does show associations between exposure to these compounds and seminal quality."

Montse Marquès · Lead researcher at IDAEA-CSIC
Infertility currently affects 15% of the global population, with male factors responsible for up to 50% of cases. The findings highlight how environmental exposures and modern lifestyles contribute to reproductive health issues.