Nearly 40% of global cancer cases could be prevented through risk factor elimination

The analysis, led by the WHO, reveals that smoking is the most significant modifiable risk factor worldwide.

Visual representation of health risk factors, such as cigarettes and alcoholic beverages, against a medical background.
IA

Visual representation of health risk factors, such as cigarettes and alcoholic beverages, against a medical background.

An international scientific study led by the World Health Organization (WHO) revealed that 37.8% of new cancer diagnoses in 2022 could have been prevented by eliminating risk factors such as tobacco and alcohol consumption.

The study, published in the journal Nature Medicine, was led by researcher Hanna Fink of the International Agency for Research on Cancer (IARC). The work analyzed 36 cancer types across 185 countries and their relationship with 30 modifiable risk factors, including infections, environmental, and occupational hazards.
The global results indicate that, of the 18.7 million new cancer cases recorded worldwide in 2022, approximately 7.1 million (37.8%) were potentially attributable to these factors. The proportion was notably higher in men (45.4%) than in women (29.7%).
Smoking was confirmed as the main contributor to new cancer cases globally, associated with 15.1% of diagnoses. This is followed by infections (10.2%), such as the human papillomavirus (HPV) or the bacterium Helicobacter pylori, and alcohol consumption (3.2%).

"The main conclusion of this study is the value of prevention to effectively reduce the burden that cancer places on our population. In the case of Spain, the data indicates that tobacco, alcohol, infectious agents, obesity, and a sedentary lifestyle are the main factors that can be avoided."

Marina Pollán · Director General of the Carlos III Health Institute
In Spain, the analysis estimates that 41.8% of cancer cases in men and 26.1% in women are attributed to external modifiable factors. For men, 28.5% of diagnoses are linked to tobacco and 5.2% to alcohol. For women, tobacco accounts for 9.9% and alcohol for 2.7%, highlighting significant opportunities for public health prevention strategies.